Activating 'energy saver' mode significantly extends lives of animals in preclinical study
Researchers have identified that activating the AMPK protein, which regulates cellular energy, can significantly extend the lifespan of various model organisms. The study suggests that targeting this pathway directly could have future anti-aging applications.
Why it matters
Advances the scientific understanding of aging and metabolic health, potentially informing future medical treatments.
edited by Sadie Harley , reviewed by Robert Egan
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:
Add as preferred source Young vs. old fruit flies. Credit: MRC Laboratory of Medical Sciences Scientists have successfully used a drug to prolong the lifespan of several species of animals, in some cases by more than 25%. The study, published in Aging Cell , found strong evidence that activating a protein that governs energy levels may help organisms live significantly longer.
Researchers from the MRC Laboratory of Medical Sciences (MRC LMS), Imperial College London, the University of Cologne and collaborating institutions used a drug to activate an important metabolic sensor in cells. They observed anti-aging effects in species including yeast, worms and flies.
Get smarter about the news
Sign up free for a feed built around what you actually care about, Dive Deeper research on any story, and the full text of every article.
Create free accountAlready have an account? Sign in