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Nature·6 min read·hard

A tumor-on-a-chip model reveals and targets reciprocal macrophage-NK cell crosstalk to advance immunotherapy screening

H
Han, Xiahe
A tumor-on-a-chip model reveals and targets reciprocal macrophage-NK cell crosstalk to advance immunotherapy screening
✦AI Summary

Researchers have developed a 'tumor-on-a-chip' platform to study the immunosuppressive interactions between macrophages and NK cells in liver tumors. This model successfully identified drug combinations that overcome resistance to immunotherapy, offering a tool for personalized cancer treatment.

Why it matters

This technology advances precision medicine by allowing researchers to test complex drug interactions in a controlled, patient-specific environment.

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Microsystems & Nanoengineering volume 12 , Article number: 295 ( 2026 ) Cite this article

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