A new class of drugs could sharpen the body’s immune response to HIV
Researchers at the 26th International AIDS Conference discussed a new class of drugs called CD4 mimetics that may help sensitize the immune system to HIV. These drugs aim to improve the body's ability to combat viral replication, potentially moving beyond current antiretroviral therapy limitations.
Why it matters
Advancements in HIV treatment research are essential for moving toward a functional or sterilizing cure for the virus.
A new class of drugs called CD4 mimetics could be used to sensitise the immune system to HIV, the 26th International AIDS Conference (AIDS 2026) in Rio de Janeiro heard last week.
It is becoming clear that broadly neutralising antibodies, whether infused as a drug or generated by a vaccine, may not be sufficient to cure HIV, or even to lead to long-term remission off antiretroviral therapy.
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