A Multicenter Retrospective Study from Burundi

A retrospective study conducted in five hospitals in Bujumbura, Burundi, found that nearly half of patients undergoing prostate surgery had incidental prostate cancer. The findings suggest a high prevalence of high-grade tumors in this population, underscoring the need for improved diagnostic protocols.
Why it matters
This research provides vital medical data for a region where prostate cancer screening and detection protocols may be under-resourced.
Background: Incidental prostate cancer refers to clinically unsuspected prostate malignancy detected after surgical treatment for presumed benign prostatic disease. This study aimed to determine the proportion of incidentally detected prostate cancer among symptomatic patients undergoing prostate surgery and to describe its pathological characteristics in a multicenter cohort from Burundi. Pati ents and Methods: We conducted a retrospective observational multicenter observational study from January 1 to December 31, 2024, including consecutive patients who underwent prostate surgery in five major hospitals in Bujumbura, Burundi. Patients with a preoperative histopathological diagnosis of prostate cancer were excluded. All surgical specimens were examined histologically, and prostatic adenocarcinoma grading was performed according to the International Society of Urological Pathology (ISUP) grading system. Results: A total of 156 patients were included, with a mean age of 69.00 years. Lower urinary tract symptoms were the most common clinical presentation, occurring in 138 patients (88.46%).
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