5 things to know before the stock market opens Wednesday

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Happy Wednesday. Don't miss CNBC's interview with Wells Fargo CEO Charlie Scharf today at 10 a.m. ET. Watch live on CNBC or CNBC+.

Stock futures are lower this morning after a losing day for all three major averages.

Here are five key things investors need to know to start the trading day:

Apple's annual product event is today, and between its new CEO's debut and expectations for a major iPhone update, it's set to be a big one.

Brent crude futures are above the $100 a barrel mark for the first time since July as the Iran war continues to escalate. U.S. Central Command said yesterday that its forces destroyed five Iranian oil tankers in response to Tehran's attempted attacks on a U.S. Navy warship.